Sarms Powder 98% Purity SR9011 CAS 1379686-29-9 For Fat Loss

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SR9011 Description

SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.

SR9011 Half-life

In a perfect world, Hyper Lean 2.0 would have a 24-hour effect, however, this is not the case.

If one could argue that the ends justify the means then this stuff would definitely qualify as inconvenience yet worth the trouble.

Food is required quite regularly, and under normal circumstances, most manage to feed and water several times daily.

Therefore, the assumption of 2-4 daily dosing is well worth the trouble.

A scoop that hold 7 mg is included with every order by default.

SR9011 dosage

The optimal dosing sr9011 was noted at a range between 20 to 30 milligrams (mg) per day.

SR9011 VS SR9009

The difference between SR9009 and SR9011 is the pharmacological effects on cancer cells and potency.

Treatments of a variety of cancer cell types with SR9009 and SR9011 (REV-ERBα and REV-ERBβ) led to significant cancer cell apoptosis without negatively impacting the healthy cells around the tumors.

Although both have tumor blocking effects, sr-9011 is the more potent of the two.

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